Drugs' influence on blood clotting measured by microfluidic device with artificial arteries

A new microfluidic method for evaluating drugs commonly used for preventing heart attacks has found that while aspirin can prevent dangerous blood clots in some at-risk patients, it may not be effective in all patients with narrowed arteries. The study, which involved 14 human subjects, used a device that simulated blood flowing through narrowed coronary arteries to assess effects of anti-clotting drugs.The study is the first to examine how aspirin and another heart attack prevention drug respond to a variety of mechanical blood flow forces in healthy and diseased arteries.



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